Vitamin B12

A healthy low fat, mostly raw, plant based diet can minimise inflammation in the body and greatly diminish the risk of developing most chronic, degenerative diseases.  But, if the body lacks vitamin B12 it may escalate inflammatory processes!

It is important to regularly test ones B12-status.  Read about:

  • how vitamin B12 affects the body,
  • what you should test for when testing for B12-status,
  • and what types of B12 supplements are best for the body if you find that you are low.

What is B12?

Vitamin B12, cobalamin, is an essential coenzyme for human beings.  It is produced by bacteria.  It can usually be found in most products of animal origin.  It is also in the earth, where it is produced by bacteria, and small concentrations of it can be found on some organic vegetables.  Generally, however, it is difficult to get sufficient amounts of B12 from a plant-based diet.

There are a number of different B12-vitamins.  We often talk about active B12 and inactive B12 analogues.

What is active and inactive B12?

Cobalamin comes in different forms.  Most of them are inactive forms.  In the picture you can see that active B12 is only a small part of the larger cobalamin group, which in itself is a part of the corroide-group.


Inactive B12 analogues cannot be used by the body.  In some cases they may actually even make it more difficult for the body to use active B12 and increase a possibly existing B12 deficiency.

In the group of active B12 analogues we have:

  • Methylocobalamin
  • Adenosylcobalamin
  • Cyanocobalamin
  • Hydroxocobalamin

In the body it is only methylocobalamin and adenosylcobalamin that are directly active.  The other forms of cobalamins, like cyanocobalamin and hydroxycobalamin can be transformed int the directly active forms.  This is why they are still called active B12.

The transportation of B12 in the body


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